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Shionogi's naldemedine performs well in first COMPOSE Phase III

This article was originally published in Scrip

Executive Summary

Shionogi's naldemedine (S-297995), an investigational peripherally acting mu-opioid receptor antagonist, has met primary and secondary endpoints in a phase III study for the treatment of opioid-induced constipation in adult patients with chronic non-cancer pain receiving opioid therapy.

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