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Insurer Incentives For Lower-Cost HIV Drugs Not Seen As Significant Threat For Gilead, ViiV

UnitedHealthcare offers HIV-infected patients a financial incentive to switch to lower-cost therapy, including generic TDF, but analysts suspect the savings won’t be enough to encourage much switching away from Gilead’s single-tablet regimens.

Pricing Strategies Infectious Diseases Commercial

Amarin's REDUCE-IT Data For Vascepa May Be Game-Changing, But Not Without Controversy

CVOT results for Amarin's fish-oil pill show an unprecedented reduction in cardiovascular deaths. While questions have been raised about an LDL increase in the placebo group, an investigator says the overall results are too good to be explained by a well-known mineral oil effect.

Cardiovascular Clinical Trials Drug Safety

Mylan/Theravance’s Yupelri Will Launch Late This Year To Address COPD Niche

Yupelri was approved by the US FDA as the first nebulized long-acting muscarinic antagonist for once-daily treatment of chronic obstructive pulmonary disease.

Respiratory Launches Approvals

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Case Study: Broad Thinking Yields Big Results

There are numerous details when considering product packaging that require both creative thinking and feature prioritization. Rather than developing a standard solution for the current need, it’s imperative to think broadly and design options that are cost-effective, simplify operations and save time and/or resources.

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Commercial Explore this Topic

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Back In Fashion? Boston’s CBO Talks Turkey On Reinvigorating Pharma’s Unwanted Assets

Constantine Chinoporos, Boston Pharmaceuticals’ CBO, talks to Scrip about its deal strategy and how it intends to build its pipeline over the next few years, liberated from the constraints of portfolio management.

Strategy Deals Leadership

Accera Sees New Potential As It Renames, Expands To Asia To Progress Alzheimer’s Asset

The US bioventure Accera, hit by a Phase III failure for its lead candidate last year, is expanding into Asia and renaming itself as it remains hopeful of progressing its core investigational asset in a targeted population of Alzheimer’s disease patients.

Singapore Business Strategies Commercial

Editas' EDIT-101 Set To Be First In Vivo CRISPR Gene-Editing Therapy In Clinic

Editas CEO says recent IND filing to treat LCA10 eye disease puts EDIT-101 on track to be first CRISPR medicine administered directly to patients. Bosley also voices relief at recent US IP court ruling.

Business Strategies Clinical Trials

Sobi Taps AstraZeneca's RSV Therapies, Both Current And Future, For US Expansion

Swedish Orphan Biovitrum gains a boost to its US commercialization infrastructure, a product to make immunology a key part of its specialty care business, and financial flexibility to seek further product acquisitions, through an RSV products deal with AstraZeneca.


Deals Infectious Diseases

Bayer Eyes More Link-Ups Like Loxo After Pipeline Blips

Litigation woes at Monsanto are casting a shadow over Bayer but despite the news of some discontinued projects, the German major sees pharma as an integral component and will keep investing in its pipeline.

Sales & Earnings Legal Issues

Celltrion Hit By Truxima Price Cut, Temporary Utilization Rate Drop

Intensifying competition in the global biosimilars space and a temporary drop in its factory utilization rate took a toll on Celltrion's earnings in the third quarter, but analysts still expect a rosy outlook next year amid the expected US launches of biosimilar rituximab and trastuzumab, and the first subcutaneous version of Remsima on the horizon in Europe.

South Korea Biosimilars

New Year Present For Takeda As Shire Close Nears?

Takeda is hoping to start 2019 with a bang, saying its huge acquisition of Shire might become a done deal as early as January 8. Speculation continues meanwhile on possible post-merger divestments to help pay down associated debt. 

Japan Business Strategies

Coherus Gears Up For January Udenyca Launch, Prices Biosimilar At 33% Discount To Neulasta

Buoyed by the market share held by biosimilars of the short-acting neutropenia drug Neupogen, Coherus hopes its Udenyca price, contracts and services will give its biosimilar a significant share of the market for the longer-acting Neulasta.

Biosimilars Launches

Policy & Regulation Explore this Topic

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‘Drastic’ Japan Price Reforms Hitting R&D Incentives, Plans - EFPIA

European research-based pharma group proposes reconsideration of Japan’s revised pricing system, warning it is already affecting corporate R&D decisions and will stifle industry investment, innovation and patient access to new therapies if incentives are not improved.

Japan Business Strategies Government Payers

AZ's Lynparza PARP Lead Likely To Lengthen With FDA Priority Review

Despite suffering a setback at the hands of NICE, AstraZeneca's ambitious plans for Lynparza have been boosted by the FDA agreeing to speed up a review of the recent SOLO-1 data which took ESMO by storm last month.

Cancer FDA

Speedy NICE Support For Eisai's Lenvima In Liver Cancer

It took NICE nearly three years to offer routine access to Lenvima for thyroid cancer but it has taken just three months from European approval to recommend the drug for advanced or unresectable hepatocellular carcinoma.

Reimbursement Cancer

China Set To Become Global Drug Innovation Center

A London conference was told that Chinese trends in modernizing healthcare and life sciences innovation will soon produce high-quality 'made in China' medicines for global export.

China Companies

Research & Development Explore this Topic

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Pipeline Watch: Phase III Print-Outs For Tivozanib, Dulaglutide And VTS-270

Pipeline Watch is a weekly snapshot of selected late-stage clinical trial events announced by pharmaceutical and biotech companies at medical and industry conferences, in financial and company presentations, and in company releases and statements.


Pipeline Watch Approvals Research & Development

INFOGRAPHIC: Sweden's Vibrant And Growing Life Sciences Landscape

Sweden's life science industry is a key component of the Scandinavian country's economy. New life science companies emerge there every year. Growing shipments to China and Japan by Swedish companies reflect the duo’s increasing importance as export markets, especially in relation to the US and the European Union. And while the UK has hitherto been regarded as a stepping stone to foreign markets, worries over what Brexit will mean for future business and opportunities is prompting players to increasingly look to the US to set up operations.

Sweden Europe

AI-Powered 'Doctor' Adds Fuel To China Digital Health Investment Fire

China’s artificial intelligence-powered healthcare ambition takes a new form, a 24-hour health clinic complete with a medicine dispenser that may eventually be coming to a city corner near you. Pharma companies are also continuing to build digital health services in the country as part of the health technology push.

China Artificial Intelligence

Gilead’s FXR Agonist Posts Questionable Results In NASH, But Offers Hope In PSC

Although GS-9674’s efficacy data don’t appear as promising as that for Intercept’s competing FXR agonist OCA, Gilead seems to be building an argument that its drug has a better combination of efficacy and safety.

Clinical Trials Liver & Hepatic