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Featured Stories

GSK Looks For New Chair To Lead It Through New Strategic Direction

GSK’s non-exec chairman steps down from the UK firm, just a month after announcing a split that will reshape the company.

Companies Leadership Strategy

Lartruvo Phase III Fail Rocks Lilly Oncology Plans

It looks like the end for Latruvo after a late-stage trial in soft tissue sarcoma patients did not confirm the overall survival benefit seen in the Phase II study that saw the Lilly drug get a speedy approval from the FDA and the EMA in 2016.

Cancer Clinical Trials Research & Development

Q4 Pharma Earnings Preview: J&J, Bristol And AbbVie

Johnson & Johnson has solid growth drivers in pharmaceuticals, but still faces an overhang related to talc controversy; Bristol's call will be dominated by the just-announced Celgene acquisition; and AbbVie will face questions about its cancer plans after expensive failure with Rova-T.

Sales & Earnings Companies Business Strategies

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Factoring the "What Ifs" into Supply Forecasting

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Commercial Explore this Topic

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Deal Watch: Celgene Makes Alliances With Kyn, Obsidian After Bristol Buyout

Just two weeks after agreeing on a merger with Bristol, Celgene is back at its own deal-making, signing cancer-focused R&D pacts with Kyn and Obsidian. Boehringer and Bioharmony collaborate on novel therapies for hospital-acquired infections, while Sanofi teams with Biomunex on bi- and multi-specific antibodies.

Business Strategies Commercial Deals

Dark Days For Sun As Governance Saga Escalates

Allegations of corporate governance lapses continued to singe Sun, but there is little clarity on which way things are headed, at least for now.

Commercial Companies India

Sun Firefights Governance Concerns

Sun has promised to implement certain changes to address corporate governance concerns that have riled investors, including “unwinding” a loan transaction and doing away with a controversial related party arrangement for domestic sales. But will that be enough for markets to "forget" allegations of lapses or "re-rate" the firm any time soon?

Commercial Companies

Aum Bets On Asia-To-Global Oncology Model

Emerging Company Profile: Singapore-based Aum Biosciences hopes to disrupt early stage oncology drug development with an Asia-pivoted model, and the fledgling firm has struck interesting alliances to progress its plans.
Singapore StartUps and SMEs

Catalan Biotechs Boosted By International Backers

The number of foreign investors participating in Catalan biotech companies has gone from 0 to 50, and over the past five years alone, the figure has increased tenfold, according to the latest Biocat report.

Spain Financing

Finance Watch: VC Deals Keep Up Fast Pace With $1.1bn In Less Than Three Weeks

Finance Watch has noted $1.1bn worth of venture capital deals so far in 2019. Meanwhile, public offerings continue to be muted by the US government shutdown, though Revance and others sold shares. Also, Five Prime and others reveal layoffs and strategic shifts.

Financing StartUps and SMEs

Spectrum Reshuffles Focus, Selling Seven Products To Aurobindo

By selling seven approved oncology/hematology products to a US affiliate of Aurobindo, Spectrum gets cash to increase focus on late-stage candidates Rolontis for neutropenia and poziotinib for solid tumors.

Cancer Commercial

Lilly/Loxo Deal Came Together Quickly

Lilly's $8bn acquisition of genetics-based cancer specialist Loxo Oncology didn't involve any other bidders and was finalized in just days over the holidays as Lilly sought to make a news splash at the J.P. Morgan Healthcare conference, according to an SEC filing.

Deals Business Strategies

Policy & Regulation Explore this Topic

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Rare But Real: How One Startup Is Willing Itself To Lift China Orphan Drug Market

As a promising market for orphan drugs, China has seen several approvals in this space in the past six months, mostly from multinationals. But Beijing-based CANbridge believes that a smaller biotech also has a good shot at a leadership role, despite a lack of funding and reimbursement and prickly pricing issues.

China Rare Diseases Policy & Regulation

Financial Transparency Concerns Over Patient Groups Advising NICE

England and Wales' cost-effectiveness agency has been urged to review its disclosure policy in a BMJ report which calls on NICE to probe the financial transparency of patient organizations that contribute to reimbursement assessments.

Reimbursement United Kingdom

Pharma Industry Holds Tight As Disorderly Brexit Approaches

A worst-case Brexit scenario – a disorderly one – has become more likely, making an already white-knuckled life sciences industry step up its preparations.

Brexit Trade

Scrip Asks...What Does 2019 Hold For Biopharma? Part 3: Pricing, Reimbursement And Market Access

How much therapies should cost and how they should be reimbursed are questions that are expected to dominate in 2019, according to industry experts and participants surveyed by Scrip on their expectations for the coming year. This is the focus for the final installment of our three-part Scrip Asks series.

Pricing Debate Pricing Strategies

Research & Development Explore this Topic

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Molecule Diversity Creates Developmental Challenges For Aspiring Commercial Biotechs

Speaking on the sidelines at BIO-Europe 2018, Jenifer Wheat, head of commercial development at Lonza’s mammalian and microbial MMBU, explains to Scrip how having a manufacturing component in their commercialization strategies can facilitate success. Even those companies not planning to launch their own products but planning to license programs to partners can benefit from support from the contract development manufacturing sector.

Strategy Manufacturing Commercial

Biotech Showcase 2019: Mimicking plants creates GI infection antibiotic alternative

Gastrointestinal infections are the number one reason for US physician visits and account for about half the $50bn in global antibiotic sales. Speaking during Biotech Showcase 2019, Alex Huang, CEO of Quellthera, described to Mike Ward how the company is developing a novel prodrug concept, which mimics plant hypersensitive responses to toxins, as a sustainable alternative to antibiotics and as an adjunctive therapy to standard of care antibiotics for treatment and prophylaxis for a range of GI infections.

Infectious Diseases Companies

Revamped Redx’s New CEO Says Porcupine Inhibitor Trials 'Now On Track'

After regulatory talks, revamped Redx gets green light to resume clinical study of RXC004 in patients with advanced solid tumors, while sister porcupine inhibitor RXC006 is set to enter IPF trials in 2020, the biotech's CEO tells Scrip.

Clinical Trials Cancer

Pipeline Watch: Phase II Results With ZGN-1061 And OMS721

Pipeline Watch is a weekly snapshot of selected late-stage clinical trial events announced by pharmaceutical and biotech companies at medical and industry conferences, in financial and company presentations, and in company releases and statements.


Pipeline Watch Approvals