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Early Promise Of NextCure’s Novel IO Candidate Continues To Fade
Lead immuno-oncology asset NC318 targeting Siglec-15 showed encouraging early activity in patients refractory to PD-1/L1 inhibitors, but now Phase II plans are scuttled in lung and ovarian cancers.
Roche's Tecentriq Disappoints In Ovarian Cancer Study
PD-1/PDL-1 inhibitors have not proved effective for ovarian cancer on their own or in combinations. Now Roche's Tecentriq, combined with the firm's blockbuster Avastin, has suffered a similar fate to Merck KGaA and Pfizer's Bavencio in failing to improve survival.
Concerns About Eye Toxicity Could Limit GSK’s Myeloma Drug Potential
Company told more measures needed to limit damage to patients' eyes caused by antibody drug conjugate.
Stockwatch: Will Coronavirus Drug Developments Rescue The Sector’s Pricing Reputation?
Can the development of coronavirus vaccines and therapeutics reverse the demonization of the pharmaceutical sector brought about by drug price increases?
Coronavirus Update: Lower Immune Responses Could See ‘Shake Out’ Of Vaccine Contenders
Leader of London university's vaccine contender hopeful of breakthrough in early 2021, but thinks Oxford's forecast of September overly optimistic.
Newly Launched Eir Ventures To Target ‘Early Nordic Opportunities’
The Nordic region’s vibrant life sciences ecosystem will be the chief focus for newly created Eir Ventures, a strategic partnership and investment company.
Atox ‘Remains On Track’ Despite ACCUTE Setback
After talking with the FDA, Atox will file an NDA for its necrotizing soft tissue infections therapy despite missing primary endpoints in a pivotal trial, the biotech’s CEO tells Scrip.
Merck To Pay Up To $425m For Foghorn’s Gene Regulation Therapies
US major continues its expansion in oncology with an early stage deal with Flagship Pioneering protegés.
Hansa Raises $121m To Fund Idefirix Launch
Having recently signed a gene therapy collaboration with Sarepta and received a positive opinion from the CHMP for its kidney transplant therapy, Sweden's Hansa has now raised a substantial sum in a "multiple times oversubscribed" placing.
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