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Scholar Rock Inc.

Niche modulators target dysregulated growth factors

This article was originally published in Start Up

Executive Summary

Scholar Rock Inc. hope to use novel antibodies, which it calls “niche modulators,” to home in on latent forms of growth factors that get stored as complexes with other proteins in the spaces between cells. The start-up’s focus in on transforming the TGF-beta family of growth factors into highly specific therapeutics.


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