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Amgen's Kyprolis bests Velcade in new Phase III myeloma trial

This article was originally published in Scrip

Executive Summary

Amgen/ Onyx's second-generation proteasome inhibitor Kyprolis (carfilzomib) has doubled progression-free survival in patients with relapsed multiple myeloma in the head-to-head ENDEAVOR trial that pitted it against Takeda's older proteasome inhibitor bortezomib (Velcade).

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