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Seattle Genetics drops under ASH cloud as PD-1s hog limelight

This article was originally published in Scrip

Executive Summary

Seattle Genetics saw its share price drop 7% on 8 December despite positive data presentations at the American Society of Hematology (ASH) annual meeting. Investors are concerned that Adcetris (brentuximab vedotin), which it is developing in collaboration with Takeda, will not fare well against competing therapies in Hodgkin lymphoma, namely the PD-1 drugs Merck & Co's pembrolizumab and Bristol-Myers-Squibb's nivolumab.



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