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Madrigal Pharmaceuticals Inc.

www.madrigalpharma.com

Latest From Madrigal Pharmaceuticals Inc.

Genfit Assesses Optimal Elafibranor NASH Combo Therapy Opportunity

As it nears the Phase III data readout for elafibranor in NASH, Genfit plans combo therapy studies to determine if a GLP-1 analog or SGLT2 inhibitor would offer the best therapeutic synergy, market potential and partnership opportunity.

Business Strategies Drug Approval Standards

CymaBay Alters NASH Hypothesis After Phase IIb Failure In Hepatic Fat Reduction

Firm points to liver biomarker findings, saying they may yield clear liver benefit at 52 weeks. Both CymaBay's and Genfit's stock prices fell as investors wondered about broader read-through for the PPAR agonist class.

Liver & Hepatic Clinical Trials

CymaBay Following The Leaders, Pursues NASH, PBC Simultaneously

Biotech thinks its PPAR delta agonist will prove much more potent than Genfit’s elafibranor from the same class and will offer a better tolerability profile than Intercept’s OCA.

Liver & Hepatic Business Strategies

NASH News & Notes From The European Liver Meeting

Non-alcoholic steatohepatitis (NASH) was a focal point of EASL’s conference. Madrigal becomes the fifth company into Phase III in NASH, but Viking’s competing THR agonist is progressing also.

Liver & Hepatic Research & Development
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