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Optherion Inc.

http://www.optherion.com

Latest From Optherion Inc.

Biotechs Eye Macular Degeneration

Spurred by the commercial success of Lucentis, start-ups developing new therapeutics for AMD tap into a growing understanding of the pathogenesis of the disease. In this issue, we profile five emerging AMD drug developers: Acucela, Iconic Therapeutics, MacuCLEAR, Ophthotech, Optherion and Sirion Therapeutics.

Optherion Inc.

Based on a growing understanding of the genetics of age-related macular degeneration and its association with the immune system, Optherion is developing a treatment that it hopes may prevent the disease from progressing into its most serious and debilitating 'wet' form.

BioPharmaceutical

Ophthotech Corp.

Ophthotech is creating drugs to be used in combination with anti-VEGF therapies for wet AMD. It is developing inhibitors of platelet-derived growth factor and the a5b1 integrin, as well as an anti-C5 receptor aptamer that could eventually be a therapy for both wet and dry forms of age-related macular degeneration.

BioPharmaceutical Platform Technologies

Start-Up Previews (07/2009)

A preview of the emerging health care companies profiled in the current issue of Start-Up. This month's profile group, "Biotechs Eye Macular Degeneration," features profiles of Acucela, Iconic Therapeutics, MacuCLEAR, Ophthotech, Optherion and Sirion Therapeutics. "Scoping Out Gastroenterology Start-Ups" features profiles of invendo medical, Mauna Kea Technologies and Softscope Medical Technologies. Plus these Start-Ups Across Health Care: Bone Solutions, Cardioxyl Pharmaceuticals, Savara and VasoNova.

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