Astellas's First-In-Class CLDN18 Antibody Meets Phase III Gastric Endpoints
Competitive Advantage Vs Opdivo?
Executive Summary
Novel candidate acquired from Ganymed in 2016 moves closer to first approval filing anywhere for a CLDN18-targeting antibody, and as a potential competitor for Opdivo in HER2-negative gastric cancer, following positive top-line Phase III results in the first-line combo setting. Results from GLOW trial in combination with CAPOX also awaited.
You may also be interested in...
Chinese Biotechs Ascend Deal-Making By Partnering Up Claudin 18.2 Agents
The recent partnerships on Claudin 18.2-targeting agents between Chinese biotechs and big pharma have brought China innovation to a new phase that Chinese firms can be proud of, an executive from Keymed Biosciences, one of the Chinese biotechs involved in such deals, tells Scrip in an interview.
Competition Grows In Claudin18.2 As AstraZeneca Seals Antibody Conjugate Deal
Already a major player in the field thanks to Enhertu, AstraZeneca is doubling down in gastric cancer with the new antibody-drug conjugate deal with China’s KYM Biosciences.
Astellas CEO Yasukawa On Gene Therapy Challenges, Deal Strategies
Despite facing two clinical holds for its gene therapy candidates, Astellas is committed to proceeding with R&D projects in this modality. Outgoing CEO Kenji Yasukawa says technical challenges have motivated the firm's recent deals with academia and bioventures, and also provided updates on other key pipeline assets in the second part of this exclusive interview with Scrip.