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Amgen’s Lumakras Efficacy Confirmed In Phase III, But Not As Strong As Phase II

ORR 28% Versus 37% In Trial Prior To Accelerated Approval

Executive Summary

Lumakras data at ESMO in KRAS G12C-mutated lung cancer bested docetaxel on PFS, and largely on safety. OS was better for chemotherapy, but the trial was not powered for statistical significance on OS.

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