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Roche Sees Glass Half Full After Ipatasertib Data

Hit One Co-Primary Endpoint, Missed The Other

Executive Summary

Roche’s ipatasertib has improved progression-free survival in a sub-group of previously untreated metastatic castration-resistant prostate cancer patients – those whose tumors had PTEN loss – in a Phase III study. However the AKT inhibitor failed to cut the risk of disease worsening or death in the broader population.

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