Incyte/Merck's ECHO-301 Failure Casts More Shadow On IDO Space
Following failure of Incyte/Merck's epacadostat/Keytruda study, NewLink Genetics says it is reviewing its IDO clinical programs.
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BMS Wins Competition For Novel Checkpoint Inhibitors With Relatlimab Approval
The LAG-3 antibody relatlimab, with Opdivo in the fixed-dose combo Opdualag and a $27,389-per-dose price, is the first approved in a new class of checkpoint inhibitors since the anti-PD-1/PD-L1s.
ASCO Offers Glimpse Of LAG-3 Inhibitors’ Potential Opportunities – And Limitations
Clinical data released on drugs targeting LAG-3 from BMS, Regeneron, Merck & Co. and Immutep in a variety of cancers.
Unhappy New Year For Incyte With Itacitinib Flop
Incyte's hopes of reducing its reliance on Jakafi have suffered a blow after a Phase III trial of itacitinib failed. The stock has slumped and analysts are raising concerns about the company's ability to generate value from its hefty R&D investments.