Biogen Forecasts Gradual Launch For Life-Transforming Drug Spinraza
The biotech said it has had some early “challenges” securing reimbursement for Spinraza, which it priced at $750,000 for the first year of treatment for the rare disease spinal muscular atrophy
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Risdiplam’s efficacy across two clinical trials and oral dosing made it a credible threat before its US FDA approval, but its weight-based pricing falls below Biogen’s Spinraza and Novartis’s Zolgensma.
The total cost of Zolgensma is more than $2m – in line with estimates – or $425,000 annually for five years if payers choose an annuity-like payment plan. Novartis is also negotiating value-based reimbursement agreements for infants treated with the one-time infusion.
The firm announced a small deal with Karyopharm for a preclinical asset with potential in ALS, but large deals are also being considered, management told the fourth quarter earnings call.