Novartis Resurrects Failed Muscle Wasting Drug In New Obesity Trial
Bimagrumab failed in a pivotal late stage clinical trial last year for an orphan muscle wasting disorder. Novartis now wants to assess its potential in obesity, an area not exactly renowned for its pharmaceutical successes.
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Novartis has won its third breakthrough therapy designation from the US FDA, which granted the status to the Swiss drug maker's investigational muscle-wasting disease drug bimagrumab (BYM338), a fully human monoclonal antibody.
The UK's main reimbursement bodies made a series of decisions this week that were broadly favorable and largely focused on oncology medicines.