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Savara Pharmaceuticals

Repurposing vancomycin to fight drug-resistant infection in CF

This article was originally published in Start Up

Executive Summary

Savara Pharmaceuticals isn’t the first company keen to develop an inhaled version of a well-known antibiotic for treating lung infections in cystic fibrosis patients. But while other companies have developed inhaled forms of antibiotics against the relatively common infectious organism Pseudomonas aeruginosa, Savara is targeting an equally dangerous bug, methicillin-resistant Staphylococcus aureus.

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Savara Inc.

Savara's NanoCluster dry powder aerosol drug delivery platform has potential for local or systemic delivery of a wide variety of drugs. Savara says that since it can precisely tailor its microparticles' sizes, it will improve aerosol efficiency, and thus will be able to deliver two to three times more drug to the lung than competitors' products.

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