Blocking Potential Brain Metastases at the Blood Brain Barrier
This article was originally published in Start Up
Executive Summary
The flip side of facilitating drug delivery through the blood brain barrier is to figure out how bad actors such as tumor cells sometimes ease through it. A research team recently identified an enzyme that helps breast cancer cells do just that. Blocking its activity could help prevent metastasis to the brain, which occurs in some 15% of breast cancer patients.