ASCO: Spotlight shines on PARP inhibitors, but no star emerges
This article was originally published in Scrip
The side effects of drugs that inhibit poly ADP-ribose polymerase (PARP) are so tolerable and their activity in BRCA-positive tumors is so remarkable that cancer patients are seeking out clinical trials and clinicians are eager to enroll women with breast and ovarian cancer in the studies.
You may also be interested in...
Tesaro Inc.'s stock price more than doubled on June 29 after the company reported positive progression-free survival (PFS) data for its PARP inhibitor niraparib in the Phase III NOVA clinical trial, which tripled PFS for some women with ovarian cancer compared with placebo – a result that lifted the values of competing firms.
ReCode, whose platform allows for organ-specific delivery of RNA therapies, plans to start clinical trials in 2022 for its two lead programs in primary ciliary dyskinesia and cystic fibrosis.
Public Company Edition: Benefitting from hope that biopharma interventions will help the coronavirus pandemic, the industry is faring better than others in the stock market, including the ability to launch IPOs. Also, BridgeBio leads recent financings and PDL is on track to dissolve by year-end.