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$100M stock pop as TH-302 approaches Threshold of success in pancreatic cancer

This article was originally published in Scrip

Executive Summary

Threshold Pharmaceutical's hypoxia-targeted drug candidate TH-302 has produced a significant 63% extension in progression-free survival in a Phase IIb study in pancreatic cancer, top-line data show. The drug was the subject of a licensing deal worth up to $525 million with Merck KGaA earlier this month (, 3 February 2012), and the share price of Threshold jumped by $2.95 to $6.45 (84%) on the news, before drifting to $5.14 by the end of 21 February 2012. The market thus valued the news of clinical success at around $100 million.

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