Fate of Avastin in early-stage cancer uncertain after second Phase III failure in colon cancer
This article was originally published in Scrip
Roche is facing further disappointment with its top selling drug, Avastin (bevacizumab) – which is so far approved for advanced/metastatic cancer in a number of tumour types – after the anti-angiogenic agent failed in its second Phase III trial in early-stage colon cancer to reduce the risk of disease recurrence. Meanwhile, the FDA has delayed its much-anticipated decision on Avastin's use in metastatic breast cancer after the company submitted new information.
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