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Gilead likely to drop darusentan on failed Phase III resistant hypertension trial

This article was originally published in Scrip

Executive Summary

Gilead Sciences looks likely to terminate development of endothelin A-receptor antagonist darusentan for resistant hypertension after the drug failed to meet its primary endpoint in a second Phase III trial. The company's share price fell by 3.5% to close at $45.31 on Nasdaq after the failure was announced on December 15th.

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