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Antisoma changes Phase III leukaemia trial primary endpoint

This article was originally published in Scrip

Executive Summary

Antisoma has amended the primary endpoint of a Phase III ACCEDE trial testing its experimental chemotherapy drug AS1413 (amonafide L-malate) - one of its two lead products - in patients newly diagnosed with secondary acute myeloid leukaemia (secondary AML), following discussions with the FDA and trial investigators.

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