DHEA fat factor

Elderly patients supplemented with DHEA for six months had significant decreases in visceral and subcutaneous fat, suggesting that "DHEA replacement may partially reverse the aging-related accumulation of abdominal fat in elderly people," a study published in the Nov. 10 JAMA found. Fifty-three participants ages 65 to 78 were randomly assigned to 50 mg DHEA or placebo. The findings "raise the possibility that long-term DHEA replacement therapy might reduce the accumulation of abdominal fat and protect against development of the metabolic/insulin resistance syndrome." The study might be limited by the small sample size and brief duration, Dennis Villareal, MD, Washington University School of Medicine, St. Louis, et al., acknowledge, recommending their results be considered preliminary...