Evidence backs surgery for BRCA1/2 women:
This article was originally published in Clinica
Executive Summary
Women with mutations in their BRCA1 and BRCA2 genes may be three times less likely to develop breast or ovarian cancer if they undergo surgery. In a prospective study of 170 patients, researchers found that the removal of the ovaries and fallopian tubes, or oophorectomy, was associated with a 75% decreased risk of subsequent breast or ovarian cancer. The study, by researchers from the Memorial Sloan-Kettering Cancer Center, in New York, appears in The New England Journal of Medicine (May 23).