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Ocelus Ltd.

This article was originally published in Start Up

Executive Summary

Ocelus Ltd. hopes to extend transdermal delivery to macromolecules. Its early-stage technology combines a microchip reservoir with microneedles that could painlessly inject precise yet tiny amounts of a drug into the skin at hundreds of sites per square centimeter. This could make administration simpler, and by reducing the pain associated with injectable drugs, improve patient compliance.

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Start-Up Previews (03/2010)

A preview of the emerging health care companies profiled in the current issue of Start-Up. This month's profile group, Transdermal Drug Delivery: More Than Skin Deep, features profiles of AllTranz, Ocelus, Quinnova and Syntropharma. Plus these Start-Ups Across Health Care: Apnex Medical, Cellular Dynamics, Helix Therapeutics, Presym and Vatrix Medical.

AllTranz Inc.

AllTranz Inc. has technology suitable for making pro-drugs out of opioids and cannabinoids, and it thinks these can be developed as treatments for a wide range of indications, from neuropathic pain to addiction, pancreatitis, and more. The company is leading, however, with a gel formulation that combines cannabidiol and penetration enhancers to treat the pain of osteoarthritis as well as strains and sprains.

Transdermal Drug Delivery: More Than Skin Deep

Start-ups continue to seize opportunities for delivering new and existing drugs transdermally. They are also poised to capitalize on next-generation technologies for delivering macromolecules through the skin. In this issue, we profile AllTranz, Ocelus, Quinnova Pharmaceuticals and Syntropharma.

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