Start-Up's monthly comprehensive review of emerging life science companies that have received venture funding during the month, including companies in the pharmaceutical, medical device, diagnostic and research instrumentation and reagent sectors.

Mithridion Inc, a drug development company in Madison, Wisconsin focusing on serious central nervous system disorders such as Alzheimer's disease and schizophrenia, has announced that it has secured $1.25 million in new funding, and that it is seeking partners for its lead drug candidates.

Swiss-based AC Immune SA is using both an immunological and a small molecule approach to tackling Alzheimer's disease. It hopes that both techniques may lead to compounds that may, by re-balancing the equilibrium between mutant and harmless forms of the protein amyloid beta, halt and perhaps even reverse the progression of the disease.

A preview of the emerging health care companies profiled in the current issue of Start-Up. This month's profile group, Addressing Alzheimer's, features profiles of Cognitive Pharmaceuticals Ltd., EnVivo Pharmaceuticals Inc., Reata Discovery Inc., Senexis Ltd. and Zapaq Inc. Plus these Start-Ups across Health Care: CoreValve SA, Lectus Therapeutics Ltd. and NeoGuide Systems Inc.