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ActivX Biosciences Inc.

Division of Kyorin Pharmaceutical Co. Ltd.
www.activx.com

Latest From ActivX Biosciences Inc.

Lundbeck Boosts US R&D Capability With $400m Abide Theraputics Bid

Danish neuroscience company plans to acquire Abide Therapeutics for $250m upfront and up to $150m in milestones to access serine hydrolase drug discovery platform.

M & A Neurology

Sosei's Drug Re-Profiling Strategy: A Three-Way Street

By going after Big Pharma's late-stage cast-offs, biotechs that want to be drug developers can lop years off the development time compared to de novo pharmaceutical discovery. The in-licensed compounds have already met, at the least, the druggability hurdle; their intellectual property is nailed down, they've passed the ADMET tests, and they're scalable. This strategy promises to maximize the assets of large company drug originators and give to younger, smaller companies access to compounds for in-licensing. However, the companies that could benefit the most from such an in-licensing strategy, the platform biotechs, often don't. The companies need compounds to move from platforms to product models, but pharma just doesn't see what these partners, based around a single technology and without a presence in the marketplace, can do for them. Now Japan's Sosei Co. Ltd. has come up with a new drug re-profiling strategy that makes licensing a three-way street; for itself, for platform biotechs and for pharmaceutical firms.
BioPharmaceutical North America

In-Licensing: Still a Difficult Model

One way for Pharma to bolster its lagging growth would be to capture some of the value of the compounds it has shelved during development. Start-ups have created technology platforms and systems biology approaches and are in place to reposition such stalled drugs in new indications, or to reformulate marketed compounds to extend the product life cycle. Nonetheless, drug firms largely remain reluctant to part even with compounds they have decided not to develop themselves. Drug makers say the issue is resources, but it is also desire. Until Big Pharma further loosens its grip on its compounds that are stalled in development, in-licensing will remain an opportunistic, case-by-case exercise, and biotechs must accept the fact that access will depend largely on advance insider knowledge of pharma firms' pipelines.
BioPharmaceutical Strategy

Activx Biosciences Inc.

Activx Biosciences Inc. is positioning itself as a second-generation proteomics company with what it claims is the first high-throughput chemistry platform for activity-based proteomics. The company aims to convert the massive amounts of raw genomics data into targets for drug discovery by using chemical probes to directly measure protein activity.
BioPharmaceutical Strategy
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Company Information

  • Industry
  • Biotechnology
    • Drug Discovery Tools
      • Genomics-Proteomics
  • Pharmaceuticals
  • Therapeutic Areas
  • Non-Specific
  • Alias(es)
  • Ownership
  • Private
  • Headquarters
  • Worldwide
    • North America
      • USA
  • Parent & Subsidiaries
  • Kyorin Pharmaceutical Co. Ltd.
  • Senior Management
  • James A Schoeneck, CEO
    JC MacRae, EVP, CFO
    Jonathan Burbaum, PhD, Exec. Dir., R&D
    Michael Dunn, EVP, Bus. Dev.
    Hugh Rosen, DPhil, Chmn. & Pres.
  • Contact Info
  • ActivX Biosciences Inc.
    Phone: (858) 558-5558
    11025 N. Torrey Pines Rd., Ste. 120
    La Jolla, CA 92037
    USA
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