Stanford University Medical Center
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A surge in mobile phone technology for health care applications in China has seen a U.S. innovator focus on an affordable way to conduct eye exams remotely in a market with one of the largest visually impaired patient populations in the world.
An increasing proportion of patients are presenting to cath labs with calcified plaque, and emerging cardiovascular interventions are driving the demand for calcium debulking technologies that are more benign than conventional atherectomy or balloon angioplasty. Shockwave Medical’s novel platform for debulking calcified plaque in vessels is based on lithotripsy, the use of mechanical energy to fracture kidney stones; the start-up believes it has a technology that’s specific for calcium and benign to healthy tissue.
Amir Belson is among the most prolific device entrepreneurs in the industry today, having launched a dozen companies in the past 12 years. Not as well-known as other physician-inventors, he combines an aggressive IP strategy with an innovative approach to early-stage financing to launch companies in a variety of clinical spaces.
Endoluminal Sciences has developed a polymer-based "active sealing" technology called ELS SEAL that can be applied to existing EVAR devices to enhance the long-term durability of the seal against the vessel wall, without increasing the device profile or impacting established delivery techniques. Its "bolt-on" technology aims to address the lethal failure mode of EVAR systems, endoleaks, as well as open up EVAR treatment to the 40% of patients who are not currently candidates for the procedure.