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Latest From Mines Management Inc.

Deal Watch: Novo Nordisk, Fauna To Explore Hibernation To Treat Obesity

A collaboration between Novo and Fauna will look at animal hibernation and genetic sequencing for hints toward novel therapies for obesity. Pfizer will use Insilico’s machine learning technology in target validation.

Deals Business Strategies

InDex's Lead TLR9 Agonist Shows Promise In Ulcerative Colitis

A Toll-like receptor-9 agonist under development by Sweden’s InDex Pharmaceuticals showed encouraging clinical responses in top-line results in patients with active ulcerative colitis not responding to other agents. Its novel mechanism of action and relatively benign side effect profile makes it a prime candidate to combine with biologic agents.

Gastrointestinal Clinical Trials

Mologen To Pursue Combinations Only After Lefitolimod’s Solo IMPALA Failure

Mologen’s CEO tells Scrip the German biotech will only pursue combination studies in future after its lead candidate lefitolimod failed as a monotherapy in a pivotal trial treating metastatic colorectal cancer patients.

Clinical Trials Commercial

Key Catalyst In August For Mologen As IMPALA Phase III Colorectal Cancer Reports

Mologen CEO says next month’s pivotal trial topline readout on its lead asset lefitolimod will be important for the German-based immunotherapy pioneer of DNA-based TLR9 agonists.

Clinical Trials Companies
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  • Pharmaceuticals
    • Vaccines
    • Drug Delivery
      • Macromolecule
  • Biotechnology
    • Gene Therapy, Cell Therapy
    • Large Molecule
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    • Minera Montanore Peru SAC