Quinnova Pharmaceuticals Inc.
This article was originally published in Start Up
Executive Summary
Quinnova Pharmaceuticals Inc.'s Proderm Technology delivery system is a water-lipid-based formulation designed to apply active ingredients to the skin for the treatment of inflammatory skin diseases. Several Proderm products are already on the market. The start-up's TwinDerm technology - a two-step, single-unit topical system that allows delivery of two products in sequence from a single pouch - is designed to make treatment simpler and more convenient, therefore improving patient compliance.
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Start-Up Previews (03/2010)
A preview of the emerging health care companies profiled in the current issue of Start-Up. This month's profile group, Transdermal Drug Delivery: More Than Skin Deep, features profiles of AllTranz, Ocelus, Quinnova and Syntropharma. Plus these Start-Ups Across Health Care: Apnex Medical, Cellular Dynamics, Helix Therapeutics, Presym and Vatrix Medical.
Ocelus Ltd.
Ocelus Ltd. hopes to extend transdermal delivery to macromolecules. Its early-stage technology combines a microchip reservoir with microneedles that could painlessly inject precise yet tiny amounts of a drug into the skin at hundreds of sites per square centimeter. This could make administration simpler, and by reducing the pain associated with injectable drugs, improve patient compliance.
AllTranz Inc.
AllTranz Inc. has technology suitable for making pro-drugs out of opioids and cannabinoids, and it thinks these can be developed as treatments for a wide range of indications, from neuropathic pain to addiction, pancreatitis, and more. The company is leading, however, with a gel formulation that combines cannabidiol and penetration enhancers to treat the pain of osteoarthritis as well as strains and sprains.