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Cytokinetics Inc.

This article was originally published in Start Up

Executive Summary

Cytokinetics seeks to exploit recent discoveries concerning the way in which the cytoskeleton structures and organizes cell activity to develop two business platforms: one in drug discovery and the other in cellular bioinformatics.

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Cytokinetics' recently signed research collaboration with GlaxoSmithKline provides some third-party validation for the three-year-old start-up's cytoskeleton-based technology platform. The deal which provides Cytokinetics with at least $50 million in committed funding, centers on the discovery and development of small molecule therapeutics that target mitotic kinesins for applications in the treatment of cancer. Cytokinetics also stands to earn substantial milestones on royalties in connection with the mitotic kinesins that are the subject of the collaboration, as well as buy-in rights on any drug candidates.

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