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Ironwood Paying $1bn For VectivBio To Extend Its GI Franchise Beyond Linzess

Phase III Data For Apraglutide Due In Late 2023

Executive Summary

Ironwood said it believes VectivBio’s once-weekly GLP-2 analog apraglutide is differentiated from Takeda’s once-daily Gattex in short bowel syndrome and could generate $1bn in peak sales.

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The Switzerland-headquartered group believes it has a potentially best-in-class GLP-2 agonist on its hands with apraglutide, which has proved effective in a subgroup of patients that do not benefit from standard of care Gattex.

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