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Reata, Kyowa Kirin End Bardoxolone CKD Development

Missed Secondary Endpoint In Japan Trial

Executive Summary

Reata was expecting positive results from a Phase III study by Japanese licensee for diabetic kidney disease after a US rejection for Alport Syndrome last year, but the US company and Asia partner Kyowa Kirin have now decided to end development in CKD indications after a missed secondary endpoint seen as critical to approval in Japan. 

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