Scrip is part of Pharma Intelligence UK Limited

This site is operated by Pharma Intelligence UK Limited, a company registered in England and Wales with company number 13787459 whose registered office is 5 Howick Place, London SW1P 1WG. The Pharma Intelligence group is owned by Caerus Topco S.à r.l. and all copyright resides with the group.

This copy is for your personal, non-commercial use. For high-quality copies or electronic reprints for distribution to colleagues or customers, please call +44 (0) 20 3377 3183

Printed By

UsernamePublicRestriction

Ocugen CEO Musunuri On Gene Therapy Candidates, The Omicron Advantage

Phase I Trials For OCU-400 Set For Q1 2022

Executive Summary

Ocugen’s mutation-agnostic candidate for retinitis pigmentosa and leber congenital amaurosis is set for Phase I trials in the US. In this exclusive audio interview, founder and CEO Shankar Musunuri speaks to Scrip about seeking partners beyond CanSino Biologics for the candidate while stressing Bharat Biotech’s COVID-19 vaccine could hold promise against the Omicron variant.

The formation of any company involves blood, sweat and tears and the story has been no different for Ocugen Inc.

In an audio interview with Scrip, founder-CEO Shankar Musunuri gives us a glimpse of the journey and shares his excitement about two gene therapy candidates for eye diseases.

OCU-400, a candidate to treat retinitis pigmentosa and a rare genetic eye disorder, leber congenital amaurosis, will soon be heading to the clinic for human trials. OCU-410 for age-related macular degeneration is still in the preclinical stage but has a larger canvas, with the disease being a leading cause of visual impairment and blindness throughout the world.

The company has tied up with Chinese firm CanSino Biologics Inc. for developing these two candidates and Musunuri shares further commercialization plans.

Meanwhile, he emphasizes the good intentions behind trying to bring Bharat Biotech’s COVID-19 vaccine Covaxin to the US and Canada. The broad immunity it has demonstrated against variants like Delta and could potentially show against Omicron might give it an edge over Pfizer Inc. and Moderna, Inc.’s mRNA vaccines, Musunuri feels.

However, what does a clinical trial hold by the US Food and Drug Administration and a delay in filing for emergency use authorization in Canada mean for the vaccine and company? Find out in this podcast.

Time Stamps

0:11 Introduction

2:17 Advice for aspiring start-ups

3:55 Memorable and forgettable parts of entrepreneurship journey

7:38 Stressors and boosters

9:19 Way forward for COVID-19 vaccine post clinical hold

15:20 Will Pfizer beat Ocugen to the 2-5 age group?

16:38 Does the Omicron variant complicate matters?

22:37 Possibility of a booster

28:02 US class action suit

28:53 Mutation-agnostic gene therapy platform

36:18 CanSino Biologics’ agreement for OCU-400 and OCU-410

39:17 Risks in gene therapy development

 

Interview with Ocugen Founder-CEO Shankar Musunuri

This and all our other podcasts are available on the Informa Pharma Intelligence channel on Apple PodcastsGoogle PodcastsSoundCloudTuneIn and Spotify Podcasts, and via smart speakers if one of these platforms has been set up as your default podcast provider.  

Related Stories

https://scrip.pharmaintelligence.informa.com/SC145448/Moderna-Co-Founder-Robert-Langers-Tips-For-Innovation

https://scrip.pharmaintelligence.informa.com/SC145501/Coronavirus-Update-Lukewarm-US-Panel-For-Molnupiravir-Inovio-Bharat-Look-At-Omicron

https://pink.pharmaintelligence.informa.com/PS145226/COVID-19-Vaccines-Ocugens-EUA-Request-For-Covaxin-In-Kids-Faces-Steep-Climb-At-US-FDA

https://scrip.pharmaintelligence.informa.com/SC144848/Can-Delta-Variant-Effectiveness-Fill-Brazil-Sized-Hole-In-Bharat-Biotechs-Prospects

https://scrip.pharmaintelligence.informa.com/SC145139/ExHilleman-CEO-On-COVID19-Vaccine-Heterologous-Boosting-Endemic-Disease

https://scrip.pharmaintelligence.informa.com/SC145104/Novartis-Doubles-Up-In-Optogenetics-With-Arctos-Buy

https://scrip.pharmaintelligence.informa.com/SC145457/Finance-Watch-Venture-Capital-Drives-Record-Breaking-Year-For-Cell-And-Gene-Therapies

 

 

Related Content

Topics

Related Companies

Latest News
See All
UsernamePublicRestriction

Register

SC145617

Ask The Analyst

Ask the Analyst is free for subscribers.  Submit your question and one of our analysts will be in touch.

Thank you for submitting your question. We will respond to you within 2 business days. my@email.address.

All fields are required.

Please make sure all fields are completed.

Please make sure you have filled out all fields

Please make sure you have filled out all fields

Please enter a valid e-mail address

Please enter a valid Phone Number

Ask your question to our analysts

Cancel