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Cortexyme Alzheimer’s Study Fails; Drug Slows Cognitive Decline In Some Patients

Subpopulation Efficacy Limited To One Of Two Primary Endpoints

Executive Summary

Atuzaginstat targets a bacteria associated with Alzheimer’s disease. The higher of two doses showed a 57% slowing in cognitive decline in the Phase II/III GAIN trial in mild to moderate patients with P. gingivalis infection confirmed by saliva test.

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