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Fresh Win For AstraZeneca/Merck & Co Pact With Koselugo Approval

First Medicine In EU For Rare Condition NF1

Executive Summary

Koselugo (selumetinib) was largely forgotten after failing Phase III trials in thyroid and lung cancer, as well as uveal melanoma, but its approval in Europe for inoperable plexiform neurofibromas in patients with neurofibromatosis type 1, which follows a US approval for the rare condition last year, has breathed new life into the once-lauded MEK 1/2 inhibitor.

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