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Beam And Verve Benefit From Buzz Around Base-Editing Therapies

Excitement Around Next-Gen Gene-Editing

Executive Summary

Companies claim their technologies provide more precise editing as they raise funds, but CRISPR companies remain in the lead.

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Lilly Looks To Tackle High Lipoprotein(a) Via Gene Editing With Verve

Deal snapshot: Verve will get $60m up front in cash and equity investment from Lilly in exchange for rights to a preclinical base-editing program targeting the LPA gene.

Verve Hits The Clinic With Gene-Edited Cholesterol-Lowering Drug

The company dosed the first patient in its study of base editor VERVE-101, a possible single-dose treatment for HeFH that joins a growing list of PCSK9-targeted therapy candidates.

Biotech Drives Base Editing Into Clinic As Big Pharma Looks On

Base editing has reached a new milestone as Beam’s lead candidate gets the green light for clinical trials, and its peer Verve Therapeutics is not far behind, while big pharma dips its toes in the water.

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