NICE Draft Guidance: Rejects Keytruda In Head & Neck Cancer, Xospata In AML
But Positive On Lynparza And Ibrance In Certain Settings
A series of decisions on anticancer drugs from the UK’s NICE will act as a reminder to drug developers excited by potential breakthroughs that health technology assessment has become an exacting filter for new medicines to pass through.
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Roche’s Tecentriq has been rejected by health technology assessment body NICE for use in small-cell lung cancer on the National Health Service. The move follows an earlier knockback for the drug in PD L1-positive triple-negative breast cancer.
Japanese company Daiichi Sankyo has its eye on first-line FLT3-ITD AML indication after rejection of relapsed/refractory plans in EU and US.
Pfizer’s Ibrance has won conditional reimbursement in England while more data is gathered to reduce some uncertainty.