Mersana Axes Lead ADC Compound, Puts All Its Eggs In NaPi2b Basket
Mersana Therapeutics has discontinued its lead candidate because of the competitive landscape surrounding HER2-targeted therapies, and will refocus on its only other clinical program, the NaPi2b-targetting ADC XMT-1536 for ovarian cancer and NSCLC.
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Following a clinical hold for its lead product, Mersana explains how it re-engineered the program and how it is developing its ADC platform further.