J&J Sees A Path Forward For Xarelto In Post-Hospital VTE Despite MARINER Failure
The company says the MARINER data combined with prior MAGELLAN results in acute medically ill patients support prophylaxis for VTE following a hospital stay in select individuals. However, there is no regulatory path forward in heart failure based on the COMMANDER HF study.
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Bayer and Johnson & Johnson's attempts the circumnavigate the world of venous thromboembolism (VTE) prevention with their oral Factor Xa inhibitor Xarelto (rivaroxaban) have hit an unexpected setback in the MAGELLAN study of medically ill patients.
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