In DMD, Summit Falls Well Short Of Peak It Hoped For
Executive Summary
Summit’s utrophin modulator, ezutromid, posted intriguing interim data in January, but failed to meet the primary and all secondary endpoints in a Phase II study. The UK firm discontinued development of ezutromid and will now focus on novel antibiotic candidates.
You may also be interested in...
Summit's Lead Antimicrobial Fails Pivotal Study, May Spark Therapeutic Shift
Ridinilazole fell short of significance in a late-stage trial, with some analysts now anticipating the company will alter its therapeutic strategy entirely.
Roche Discontinues Duchenne Hope At Interim Analysis
Roche is to discontinue its RG6206 clinical development program in Duchenne muscular dystrophy after an interim analysis of the Phase II/III SPITFIRE study indicates the compound would be “highly unlikely” to show a clinical benefit.
Summit Looking To Secure Superiority Claim For Ridinilazole Over Vancomycin In C. Diff
Company’s Phase III program is attempting to replicate Phase II efficacy data showing superiority for curing Clostridium difficile infections and preventing recurrence, while also compiling health economics data.