Interview: CellCentric Prostate Cancer Drug Promises Much
The Cambridge-based company's CEO Will West tells Scrip that CCS1477 has shown a lot of potential for patients with late-stage prostate cancer who are resistant to second-line anti-androgen drugs like Zytiga and Xtandi and the $26m it has just raised will help fund development of the epigenetic therapy up to Phase IIb.
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Takeda has licensed an epigenetic programme from UK firm CellCentric with a primary focus on cancer. The deal, which includes an upfront payment, preclinical and clinical milestones, and royalties on any future products, could be worth more than $200 million to CellCentric over the course of the agreement.
The French company's hopes of joining Aimmune's Palforzia on the peanut allergy market soon have been shattered after US regulators issued a complete response letter to its Viaskin Peanut patch. A lot now depends on how much work DBV will have to do to satisfy the FDA.