Alexion’s Son of Soliris Aims To Takes Dosing Right Down
Alexion is setting its sights on eight-weekly dosing for its follow-up candidate to its blockbuster Soliris, testing this schedule in its new Phase III trial in patients with paroxysmal nocturnal hemoglobinuria (PNH), based on new Phase I/II data just presented at the ASH meeting in San Diego.
You may also be interested in...
Updates from the holiday season include a Phase III failure for Pfizer's MRSA vaccine, AbbVie's submission of upadacitinib for rheumatoid arthritis and several year-end US approvals and FDA actions.
Alexion has been recognized mainly as the marketer of Soliris since 2007, but in just eight weeks the rare disease specialist added two new drugs to its commercial portfolio. Management also laid out an impressive early- to mid-stage pipeline during its first-ever investor day, suggesting the company is well positioned for long-term growth.
Daiichi Sankyo and AstraZeneca’s ambitions to expand the use of their HER-2 targeted antibody-drug conjugate product beyond breast cancer are looking realizable on the back of new results presented at ASCO, but toxicities remain an issue.