Regeneron Partnering With Ocular May Provide Needed Tech Validation
Regeneron is partnering with the troubled ophthalmology-focused biotech to develop a sustained-release formulation of Eylea that could enable a less-frequent dosing regimen.
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Ocular Therapeutix will work with Regeneron to create a sustained-release formulation of aflibercept for the treatment of wet age-related macular degeneration and other serious retinal diseases. On the same day, UroGen announced plans to work with Allergan on a hydrogel for controlled release delivery of drugs to the bladder.
Most of the significant deal-making action during the past week took place in Asia as Piramal made a play to increase its injectables business, an Eisai affiliate out-licensed rights to ovarian cancer candidate farletuzumab, and EpimAb and Kymab agreed to collaborate on bispecific antibody therapeutics.
Ocular Therapeutix Inc.'s stock plummeted 42% on June 6 after a second Phase III study of its allergic conjunctivitis therapy, Dextenza (sustained-release dexamethasone), failed to reach its single primary endpoint – another big hit for the drug following a Phase III failure in ocular inflammation in 2015.