RXi Thinks Self-Delivering RNAi Could Be The Ticket In A Tricky Field
Biotech's asymmetrical, shorter RNAi therapeutics are water-soluble and therefore can be self-delivering. Lead candidate RXI-109 is being studied in both hypertrophic and retinal scarring, but the firm has new funding that could help it move into oncology.
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RXi thought it had solved the RNAi delivery issue but was focused on dermatology and ophthalmology. New CEO Dispersyn thought the platform offered more lucrative promise as a way of optimizing IO therapy.
Fortress Biotech’s subsidiary will add the lentiviral gene therapy now in pair of Phase I/II trials to its pipeline. RXi partners with Karolinska to advance its self-delivering RNAi technology, while Avalon enlists Weill Cornell to enhance its CAR-T capabilities.
RNAi focused biotech, RXi Pharmaceuticals, has appointed Dr Geert Cauwenbergh president and CEO and a member of the board of directors. Dr Cauwenbergh was most recently chair and CEO of Barrier Therapeutics.