Glucokinase Activation Gets Boost With vTv Therapeutics' Phase II Data
vTv Therapeutics has released promising top-line data for its novel diabetes therapy TTP399, the leading product in a tricky new class of glucokinase activators, but the magnitude of the effect is still unclear and progress to Phase III awaits a partnering program.
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Phase III Will Be Real Test For vTv's Resurrected Alzheimer's Drug
Phase IIb data for vTv Therapeutics' lead product azeliragon have demonstrated an effect on cognitive deterioration in mild Alzheimer’s disease patients – but is this evidence enough to get the small biotech back on track after it lost Pfizer Inc. as a partner for the drug in 2012?
ASCO - Servier’s Vorasidenib Puts The Brakes On Brain Cancer In INDIGO
Servier’s targeted therapy, vorasidenib, can effectively delay the need for more drastic treatment in patients with low-grade glioma, but increases in liver enzymes including two cases of Hy’s law have cast some shade over the INDIGO data.
Oncology’s Hold Over The Pharma Pipeline Increases As Growth Slows
The rate of growth of the pharma pipeline slowed last year as oncology and rare diseases tightened their grip on R&D. There are also further signs of China’s rise in importance in the industry.