Sourcing therapeutic antibodies from rabbits, stabilizing them with human scaffolds
This article was originally published in Start Up
Swiss start-up Numab AG’s discovery platform includes a method of generating diverse antibodies by immunizing rabbits. Antibodies produced in this species are widely used for diagnostic purposes, and appreciated for their “high affinity,” but few companies have ever pursued rabbits as a source of therapeutic antibodies, largely because they have been difficult to isolate; Numab appears to have figured out an elegant way to do so.
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