Developing a glucose-responsive insulin with liposomes, linkers
This article was originally published in Start Up
Sensulin LLC aims to treat diabetes by linking a liposome-encapsulated form of recombinant human insulin with a boronic-acid derivative that is a competitive binder with glucose. If the drug works as envisioned, it would reduce the risk of hypoglycemia that can occur when glucose levels fluctuate during the day, and would also obviate the need for multiple injections and constant monitoring.
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