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Convoy Therapeutics Inc.

Delivering large molecule dermatology drugs through the skin

This article was originally published in Start Up

Executive Summary

Convoy Therapeutics Inc.’s SPACE platform for delivering large molecule drugs through the skin is based on a class of peptides that associate with keratin proteins, and the peptides get passed from one to the other until they diffuse across the outer layer of skin. The peptides can be formulated to envelop drug molecules. Convoy is using drugs that are already FDA approved, and because they have not been chemically modified, the FDA will not require additional clinical trials. The company’s first product delivers the immune-modulating drug cyclosporine for the treatment of moderate to severe psoriasis.

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