A New Receptor-Binding Role For MicroRNAs In Cancer
This article was originally published in Start Up
Executive Summary
A research team has identified a new role for microRNAs, the small pieces of noncoding RNA that can influence gene expression. They show that miRNAs generated in solid tumors will infiltrate into nearby cells, binding with a toll-like receptor and promoting chronic inflammation – a hallmark of the spread of many solid tumors. The researchers believe they will be able to identify a drug target and small molecules that can block the miRNA-TLR binding interaction, offering up a novel treatment strategy for cancer and possibly other diseases characterized by chronic inflammation.
You may also be interested in...
Understanding How To Develop BTK Inhibitors In MS Is Evolving
Having a reversible BTK inhibitor in the multiple sclerosis armamentarium could be the best way to favorably impact the treatment landscape.
Science Matters: Setting The Stage For Using Wearables In Oncology Drug Development
Digital biomarkers using data collected with wearable devices are making their way into clinical trials, largely in cardiovascular, respiratory and rare disease settings around physical activity metrics.
Science Matters: Setting The Stage For Using Wearables In Oncology Drug Development
Digital biomarkers using data collected with wearable devices are making their way into clinical trials, largely in cardiovascular, respiratory and rare disease settings around physical activity metrics.