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Fedora Pharmaceuticals Inc.

Developing a second-generation beta-lactamase inhibitor

This article was originally published in Start Up

Executive Summary

In recent decades, both gram-positive and gram-negative bacteria previously susceptible to beta-lactam antibiotics have developed enzymes that render them inactive. Fedora Pharmaceuticals Inc. believes it has identified compounds that may prove able to thwart all four classes of beta-lactamases. Its compounds are meant to be used in combination with existing beta-lactam antibiotics that were historically effective but are no longer.

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